PROTEUS – Creating Distributed Maintenance Systems through an Integration Platform

International audienceThis paper is based on the results from the project PROTEUS sponsored by the French Ministry of Economy, Finance and Industry and the Federal Ministry of Education and Research of Germany under the label of European Commission Initiative ITEA. It presents the architecture and the basic concepts of an integration platform, which constitutes the framework of systems implementing the tasks dedicated to remote maintenance, as well as other applications, for large and medium scale industrial installation. The approach illustrated here is useful for executing any maintenance strategy by implementing the relevant means for controlling workflow between several system components as well as the component's integration itself. The paper first points out the need for designing such a maintenance-oriented platform, continues with a requirements analysis to a global maintenance system followed by the description of the fundamentals of a maintenance application integration system. Finally a sample implementation of a maintenance scenario is given

Migration of industrial process control systems into service oriented architecture

The procedure of migrating SCADA and DCS func- tionality of the isa95 process automation architecture to a Service based automation architecture is discussed. Challenges in such migration are discussed and defined. From here the necessary migration technology and procedures are proposed. The critical migration technology is based on the mediator concept. The migration procedure is based on a functionality perspective and comprises four steps: initiation, configuration, data processing and control execution. Its argued that these steps are necessary for the successful migration of DCS and SCADA functionality in to the automation cloud.Validerad; 2012; 20120724 (jerker

Anastrozole versus tamoxifen for the prevention of locoregional and contralateral breast cancer in postmenopausal women with locally excised ductal carcinoma in situ (IBIS-II DCIS): a double-blind, randomised controlled trial

Background Third-generation aromatase inhibitors are more effective than tamoxifen for preventing recurrence in postmenopausal women with hormone-receptor-positive invasive breast cancer. However, it is not known whether anastrozole is more effective than tamoxifen for women with hormone-receptor-positive ductal carcinoma in situ (DCIS). Here, we compare the efficacy of anastrozole with that of tamoxifen in postmenopausal women with hormone-receptor-positive DCIS. Methods In a double-blind, multicentre, randomised placebo-controlled trial, we recruited women who had been diagnosed with locally excised, hormone-receptor-positive DCIS. Eligible women were randomly assigned in a 1:1 ratio by central computer allocation to receive 1 mg oral anastrozole or 20 mg oral tamoxifen every day for 5 years. Randomisation was stratified by major centre or hub and was done in blocks (six, eight, or ten). All trial personnel, participants, and clinicians were masked to treatment allocation and only the trial statistician had access to treatment allocation. The primary endpoint was all recurrence, including recurrent DCIS and new contralateral tumours. All analyses were done on a modified intention-to-treat basis (in all women who were randomised and did not revoke consent for their data to be included) and proportional hazard models were used to compute hazard ratios and corresponding confidence intervals. This trial is registered at the ISRCTN registry, number ISRCTN37546358. Results Between March 3, 2003, and Feb 8, 2012, we enrolled 2980 postmenopausal women from 236 centres in 14 countries and randomly assigned them to receive anastrozole (1449 analysed) or tamoxifen (1489 analysed). Median follow-up was 7·2 years (IQR 5·6–8·9), and 144 breast cancer recurrences were recorded. We noted no statistically significant difference in overall recurrence (67 recurrences for anastrozole vs 77 for tamoxifen; HR 0·89 [95% CI 0·64–1·23]). The non-inferiority of anastrozole was established (upper 95% CI <1·25), but its superiority to tamoxifen was not (p=0·49). A total of 69 deaths were recorded (33 for anastrozole vs 36 for tamoxifen; HR 0·93 [95% CI 0·58–1·50], p=0·78), and no specific cause was more common in one group than the other. The number of women reporting any adverse event was similar between anastrozole (1323 women, 91%) and tamoxifen (1379 women, 93%); the side-effect profiles of the two drugs differed, with more fractures, musculoskeletal events, hypercholesterolaemia, and strokes with anastrozole and more muscle spasm, gynaecological cancers and symptoms, vasomotor symptoms, and deep vein thromboses with tamoxifen. Conclusions No clear efficacy differences were seen between the two treatments. Anastrozole offers another treatment option for postmenopausal women with hormone-receptor-positive DCIS, which may be be more appropriate for some women with contraindications for tamoxifen. Longer follow-up will be necessary to fully evaluate treatment differences

A System of Systems view on Collaborative Industrial Automation

Abstract—Industrial systems are increasingly integrating Internet and other emergent technologies, concepts, methods and tools, coming from the IT world, such as cloud- or service-based approaches. As a first main consequence, the industrial automation landscape is also increasing in complexity, presenting new challenges for engineers and practitioners. Examples include dealing with evolvable heterogeneous structures that do not appear fully formed and where functions and purposes are added, removed or modified along the life cycle; as well as managing emergent properties and behaviours of entire systems, e.g. resulting from integrating new systems being not localized to any single system component. Although the component systems keep their operational and managerial independence, when they are interconnected and integrated, collaboration, cooperation and competition relationships, appear all along three major collaboration axes (lifecycle, value chain and enterprise), which should be understood, controlled and managed. In this work an effort to examine those systems under the prism of System of Systems approach, and address first recommendations to determine architectures, evolutionary steps, benefits, roadblocks as well as migration approaches that need to be followed is presented. Keywords—industrial collaborative automation; cloud-based systems; service oriented architecture; web services I

PROTEUS providing a concept for integrating online data into global maintenance strategies

Colloque avec actes et comité de lecture. Internationale.International audienceThis paper presents the basic concepts for integrating online data into distributed maintenance applications. The results presented are part of and driven by the requirements on the PROTEUS project, which consists in designing and modelling of a distributed network oriented platform for integration of maintenance applic ations. The presentation starts with a brief overview of the overall project and is mainly focused on describing the way of integrating data coming from automation equipment into maintenance strategies